I live in a subtropical area.
Short answer: YES!!.
I now religiously use a filament dryer, VAC bags and loose silica beads that I bag my self into DIY teabags and then redry in the oven.
I also make sure to dry new filament for 24hours before using it the first time…
Since I started doing this for PLA and PETG, many of my previous my print issues dissapeared…
Textured print surface and enclosure a must for me.
Prusament PETG I use the Prusa PETG profile (230-240 nozzle, 85-90 bed). (First layer - remaining print)
Overture PETG I’ve found I need 250-260 nozzle and 85-90 bed, but had to decrease retraction, increase deretraction and increase flow rate to 1.01
The only thing that I can see is out of hand is the open air filament storage! (I live in the tropics so vacbags and dessicant are a must!)
BlazeCut Tseries 50cm is about right for a 3d printer enclosure volume.
https://blazecut.com/t-series/
Prusa sells a 30cm one as an option for their enclosure, but it is undersized for the enclosure volume, so I bought the 50cm one separately.